Diverging roles of TRPV1 and TRPM2 in warm-temperature detection

The perception of innocuous temperatures is crucial for thermoregulation. The TRP ion channels TRPV1 and TRPM2 have been implicated in warmth detection, yet their precise roles remain unclear. A key challenge is the low prevalence of warmth-sensitive sensory neurons, comprising fewer than 10% of rod...

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Bibliographic Details
Main Authors: Muad Y Abd El Hay, Gretel B Kamm, Alejandro Tlaie Boria, Jan Siemens
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/95618
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