Ultrasensitive CRISPR/Cas12a-Based System for Detection of <i>Bla</i><sub>OXA-1</sub> Gene in Antibiotic-Resistant Microorganisms

Ultrasensitive CRISPR/Cas12a-Based System for Detection of <i>Bla</i><sub>OXA-1</sub> Gene in Antibiotic-Resistant Microorganisms

The <i>bla</i><sub>OXA-1</sub> gene encodes an oxacillin-hydrolyzing beta-lactamase of extended-spectrum beta-lactamase (ESBL)-producing microorganisms. The <i>bla</i><sub>OXA-1</sub> gene is found in the resistomes of some <i>Enterobacteriaceae&...

Full description

Saved in:

Bibliographic Details
Main Authors:	Marina Tyumentseva, Aleksandr Tyumentsev, Anna Prelovskaya, Andrey Akinin, Yulia Mikhailova, Andrey Shelenkov, Anna Panevina, Vasiliy Akimkin
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Series:	Current Issues in Molecular Biology
Subjects:	antibiotic-resistant microorganisms ESBL <i>bla</i><sub>OXA-1</sub> PCR CRISPR/Cas12a detection
Online Access:	https://www.mdpi.com/1467-3045/47/4/238
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Whole Genome Analysis of <i>Proteus mirabilis</i> in a Poultry Breeder Farm Reveals the Dissemination of <i>bla</i><sub>NDM</sub> and <i>bla</i><sub>CTX-M</sub> Mediated by Diverse Mobile Genetic Elements
by: Haibin Hu, et al.
Published: (2025-03-01)

blaOXA, blaSHV-, and blaTEM- extended-spectrum β-lactamases in Gram-negative strains from burn patients in Lahore, Pakistan
by: Muhammad H Haider, et al.
Published: (2020-12-01)

Genomic Insights into Colistin and Tigecycline Resistance in ESBL-Producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Harboring <i>bla</i><sub>KPC</sub> Genes in Ecuador
by: David Ortega-Paredes, et al.
Published: (2025-02-01)

Co-existence of two blaNDM-5 and blaOXA-181 on distinct plasmids in a carbapenem-resistant Klebsiella pneumoniae from a tertiary hospital, Tanzania
by: Lawrence Mapunda, et al.
Published: (2025-03-01)

Emergence of Salmonella enterica carrying blaOXA-181 carbapenemase gene, Italy, 2021 to 2024
by: Stefano Pongolini
Published: (2025-04-01)

Antimicrobial Susceptibility of Commensal <i>Escherichia coli</i> from Pig Fecal Samples and Enhanced Sensitivity for Direct Detection of the <i>bla</i><sub>CTX-M</sub> Gene by Nested PCR
by: Nutchaba Suchanta, et al.
Published: (2024-09-01)

Dissemination of ST101 blaOXA-48 producing Klebsiella pneumoniae at tertiary care setting
by: Hadir ElMahallawy, et al.
Published: (2018-06-01)

Identification of blaESBL- and blaCARBA- Positive Multi-Drug Resistant Mixta calida Isolates from Distinct Human Hosts
by: Francesca McDonagh, et al.
Published: (2025-09-01)

Different effects of plasmids harboring blaOXA-232 between major and minor clones in Klebsiella pneumoniae
by: Yun Young Cho, et al.
Published: (2025-08-01)

Antimicrobial resistance and phylogenetic lineages of KPC-2-producing blood-borne Klebsiella pneumoniae subsp. pneumoniae from Kolkata, India during 2015–2024: Emergence of Klebsiella pneumoniae subsp. pneumoniae with blaKPC-2, blaNDM, and blaOXA-48-like triple carbapenemases
by: Gourab Halder, et al.
Published: (2025-08-01)

Genetic Environments of bla<sub>CTX-M</sub> Genes Located on Conjugative Plasmids of Enterobacteriaceae Nosocomial Isolates Collected in Russia within 2003-2007
by: N. K. Fursova, et al.
Published: (2020-05-01)

Anchoring and Catalytic Performance of Co@C<sub>2</sub>N Monolayer for Rechargeable Li-Se<i><sub>x</sub></i>S<i><sub>y</sub></i> Batteries: A First-Principles Calculations
by: Xiaojing Li, et al.
Published: (2024-11-01)

Evaluation of blaOXA-48-like point mutation carbapenemase-producing Enterobacterales in Prapokklao Hospital, Thailand
by: Sirijan Santajit, et al.
Published: (2024-12-01)

Detection of a new bla OXA-51-Like variant (bla OXA-1328 ) and a novel sequence type (ST3457/2790) in Acinetobacter baumannii isolated from community sewage and an incinerator surface in Nigeria
by: Khalifa Jamil Saleh, et al.
Published: (2025-08-01)

Genomic insights into a multidrug-resistant pandoraea apista clinical isolate carrying blaOXA-153 from China
by: Lirong Li, et al.
Published: (2025-03-01)

Increased blaOXA-23-like prevalence in Acinetobacter baumannii at a tertiary care center in Lebanon (2007-2013)
by: Souha S Kanj, et al.
Published: (2018-04-01)

Identical Neighbor Structure: Effects on Spectrum and Independence in <i>CN</i><sub>s</sub> Cartesian Product of Graphs
by: Subha A B, et al.
Published: (2025-03-01)

Interrelation Between Pathoadaptability Factors and Crispr-Element Patterns in the Genomes of <i>Escherichia coli</i> Isolates Collected from Healthy Puerperant Women in Ural Region, Russia
by: Yulia Mikhaylova, et al.
Published: (2024-11-01)

Nanosecond Breakdown Characteristics of <i>C</i><sub>4</sub><i>F</i><sub>7</sub><i>N</i> and Various Mixtures at Pressures Above 1 Atmosphere in Comparison with <i>SF</i><sub>6</sub>
by: Luke Silvestre, et al.
Published: (2024-12-01)

Distribution of carbapenemase-producing and colistin resistant Acinetobacter baumannii isolates in Batna hospitals, Algeria
by: Asma Bouali, et al.
Published: (2025-07-01)

Commutators of Pre-Lie <i>n</i>-Algebras and <i>PL</i><sub>∞</sub>-Algebras
by: Mengjun Wang, et al.
Published: (2025-05-01)

Genomic epidemiology and characterization of difficult-to-treat resistant Pseudomonas aeruginosa isolates co-harboring bla OXA-50 and crpP causing bronchiectasis
by: Lulu Jin, et al.
Published: (2025-04-01)

Biosynthesis and Characterization of Mn<sub>3</sub>O<sub>4</sub> Nanoparticles Using <i>Bixa orellana</i> and <i>Nerium oleander</i> Leaf Extracts at Low Temperature and Neutral pH
by: Eiser Valle-Rivera, et al.
Published: (2025-02-01)

Electrostatic Self-Assembly of Heterostructured In<sub>2</sub>O<sub>3</sub>/Ti<sub>3</sub>C<sub>2</sub>T<i><sub>x</sub></i> Nanocomposite for High-Selectivity NO<sub>2</sub> Gas Sensing at Room Temperature
by: Yongjing Guo, et al.
Published: (2025-07-01)

A <i>TM</i><sub>01</sub>-<i>TE</i><sub>11</sub> Circular Waveguide Mode Converter on the Basis of Dielectric Filling
by: Zibin Weng, et al.
Published: (2025-05-01)

Serogrouping and Molecular Characterization of ESBL-Producing Avian Pathogenic <i>Escherichia coli</i> from Broilers and Turkeys with Colibacillosis in Algeria
by: Nadia Safia Chenouf, et al.
Published: (2025-03-01)

Novel allelic variants of blaOXA-48-like carried on IncN2 and IncC2 plasmids isolated from clinical cases in Argentina: In vivo emergence of blaOXA-567
by: Juan Manuel de Mendieta, et al.
Published: (2025-03-01)

Insights on Polyidide Shuttling of Zn-I<sub>2</sub> Batteries by I<sub>3</sub><sup>−</sup>/I<sup>−</sup> Electrolytes Based on the Dual-Ion Battery System
by: Xingqi Chang, et al.
Published: (2025-05-01)

Stochastic <i>H</i><sub>∞</sub> Filtering of the Attitude Quaternion
by: Daniel Choukroun, et al.
Published: (2024-12-01)

Companion Animals as Reservoirs of Multidrug Resistance—A Rare Case of an XDR, NDM-1-Producing <i>Pseudomonas aeruginosa</i> Strain of Feline Origin in Greece
by: Marios Lysitsas, et al.
Published: (2025-06-01)

Effect of BaO Content on the Photoluminescence Properties of Mn<sup>2+</sup> and Eu<sup>2+</sup>-Codoped Sr<sub>3−<i>x</i></sub>Ba<i><sub>x</sub></i>MgSi<sub>2</sub>O<sub>8</sub> Phosphors
by: Shu-Han Liao, et al.
Published: (2025-06-01)

On <i>D<sub>α</sub></i>-Spectrum of the Weakly Zero-Divisor Graph of ℤ<i><sub>n</sub></i>
by: Amal S. Alali, et al.
Published: (2025-07-01)

Genetic Parameter Estimation of Body Weight and <i>Vp</i><sub>AHPND</sub> Resistance in Two Strains of <i>Penaeus vannamei</i>
by: Guixian Huang, et al.
Published: (2025-04-01)

Composite ZIF-8 with Cs<sub>3</sub>Bi<sub>2</sub>I<sub>9</sub> to Enhance the Photodegradation Ability on Methylene Blue
by: Tao Tang, et al.
Published: (2025-03-01)

<i>H</i><sub>∞</sub> Filtering of Mean Field Stochastic Differential Systems
by: Siqi Lv, et al.
Published: (2024-10-01)

Vapor-Assisted Method to Deposit Compact (CH<sub>3</sub>NH<sub>3</sub>)<sub>3</sub>Bi<sub>2</sub>I<sub>9</sub> Thin Films for Bismuth-Based Planar Perovskite Solar Cells
by: Zihao Gao, et al.
Published: (2025-02-01)

<i>H</i><sub>∞</sub> Consistency of T-S Fuzzy Supply Chain System Based on Trust Mechanism
by: Yong Huang, et al.
Published: (2024-12-01)

<i>V<sub>a</sub></i>-Deformed Free Convolution
by: Fahad Alsharari, et al.
Published: (2025-02-01)

THE STUDY OF THE LUMINESCENCE PROPERTIES OF Y<sub>0.85‑ <i>x</i></sub>Yb<sub>0.15</sub>Er <i><sub>x</sub> </i>Al<sub>3</sub>(BO<sub>3</sub>)<sub>4</sub>
by: Sergey Vladimirovich Kostyukov, et al.
Published: (2022-05-01)

Growth and Characterization of Ga<sub>2</sub>O<sub>3</sub> for Power Nanodevices Using Metal Nanoparticle Catalysts
by: Badriyah Alhalaili, et al.
Published: (2025-07-01)