Ultrasensitive CRISPR/Cas12a-Based System for Detection of <i>Bla</i><sub>OXA-1</sub> Gene in Antibiotic-Resistant Microorganisms

Ultrasensitive CRISPR/Cas12a-Based System for Detection of <i>Bla</i><sub>OXA-1</sub> Gene in Antibiotic-Resistant Microorganisms

The <i>bla</i><sub>OXA-1</sub> gene encodes an oxacillin-hydrolyzing beta-lactamase of extended-spectrum beta-lactamase (ESBL)-producing microorganisms. The <i>bla</i><sub>OXA-1</sub> gene is found in the resistomes of some <i>Enterobacteriaceae&...

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Bibliographic Details
Main Authors: Marina Tyumentseva, Aleksandr Tyumentsev, Anna Prelovskaya, Andrey Akinin, Yulia Mikhailova, Andrey Shelenkov, Anna Panevina, Vasiliy Akimkin
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Current Issues in Molecular Biology
Subjects:
antibiotic-resistant microorganisms
ESBL
<i>bla</i><sub>OXA-1</sub>
PCR
CRISPR/Cas12a
detection
Online Access:https://www.mdpi.com/1467-3045/47/4/238
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