Aryl Itaconic Acids from Aryl Aldehydes and (Triphenylphosphoranylidene)succinic Anhydride via a One-Pot Ring-Opening–Wittig Olefination–Hydrolysis Reaction

Aryl Itaconic Acids from Aryl Aldehydes and (Triphenylphosphoranylidene)succinic Anhydride via a One-Pot Ring-Opening–Wittig Olefination–Hydrolysis Reaction

(Triphenylphosphoranylidene)succinic anhydride, which is prepared from triphenylphosphine and maleic anhydride and is itself not reactive towards aryl aldehydes, is ring-opened with methanol to methyl (triphenylphosphoranylidene)succinate. In one pot, the newly formed phosphorane is reacted with ary...

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Bibliographic Details
Main Authors: Vijo Poulose, Salama Almheiri, Noura Alwahedi, Arwa Alzeyoudi, Maryam Aghaei, Sreeraj Gopi, Thies Thiemann
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Chemistry Proceedings
Subjects:
itaconic acids
one-pot synthesis
Wittig reaction
anti-bacterial studies
Online Access:https://www.mdpi.com/2673-4583/16/1/37
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