Multi-omics-based construction of a palmitoylation-driven prognostic model reveals tumor immune phenotypes in osteosarcoma

Multi-omics-based construction of a palmitoylation-driven prognostic model reveals tumor immune phenotypes in osteosarcoma

Abstract Background Osteosarcoma (OS), the leading primary malignancy of bone in adolescents, is known for its aggressive metastatic behavior and poor responsiveness to conventional therapies. As a lipid-mediated post-translational modification, protein palmitoylation has gained attention for its pi...

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Bibliographic Details
Main Authors: Jingyu Chen, Feihu Chen, Haiping Zhang, Yuanlong Hu, Xingyu Zhou, Xijia Weng, Guofeng Bao, Xiaomin Ding
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Osteosarcoma
Palmitoylation
Prognostic signature
Single-cell RNA sequencing
Tumor microenvironment
Online Access:https://doi.org/10.1007/s12672-025-03364-8
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https://doi.org/10.1007/s12672-025-03364-8

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