Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia

Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may represent a target for treatment. Toll-like receptor-4 (TLR4), toll-like receptor-2 (TLR2), myeloid differentiation factor 88 (MyD88), and nuclear factor kappa-B (NF-κB) have been linked to inflammatory reactions....

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Bibliographic Details
Main Authors: Hongguang Fan, Litao Li, Xiangjian Zhang, Ying Liu, Chenhui Yang, Yi Yang, Jing Yin
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2009/704706
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