Effect of low-dose primaquine treatment on Plasmodium vivax recurrence and transmission-blocking activity in southwest Ethiopia: a longitudinal cohort study

Effect of low-dose primaquine treatment on Plasmodium vivax recurrence and transmission-blocking activity in southwest Ethiopia: a longitudinal cohort study

Abstract Background Existing malaria control strategies for Plasmodium vivax are challenging due to its dormant and relapsing liver stages, as well as the early onset of gametocytogenesis. Primaquine (PQ) effectively eliminates dormant stages and can kill gametocytes; however, it necessitates repeat...

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Bibliographic Details
Main Authors: Hallelujah Getachew, Kassahun Habtamu, Ashenafi Abossie, Assalif Demissew, Arega Tsegaye, Teshome Degefa, Daibin Zhong, Xiaoming Wang, Guofa Zhou, MingChieh Lee, James W. Kazura, Christopher L. King, Delenasaw Yewhalaw, Guiyun Yan
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Malaria Journal
Subjects:
Plasmodium vivax
Recurrent
Chloroquine
Primaquine
Transmission-blocking activity
Online Access:https://doi.org/10.1186/s12936-025-05365-y
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https://doi.org/10.1186/s12936-025-05365-y

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