Synthesis and Reactivity of Oligo(ethylene glycol)-Tethered Morita–Baylis–Hillman Dimers in the Formation of Macrocyclic Structures Showing Remarkable Cytotoxicity

Synthesis and Reactivity of Oligo(ethylene glycol)-Tethered Morita–Baylis–Hillman Dimers in the Formation of Macrocyclic Structures Showing Remarkable Cytotoxicity

<b>Background/Objectives</b>: Crown ethers have received increasing interest owing to their ability to form stable complexes with cations. This molecular feature has been successfully exploited in the development of biologically relevant ionophores. <b>Methods</b>: In order t...

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Bibliographic Details
Main Authors: Marco Paolino, Mario Saletti, Jacopo Venditti, Arianna Zacchei, Alessandro Donati, Claudia Bonechi, Germano Giuliani, Stefania Lamponi, Andrea Cappelli
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
macrocyclic compounds
crown ethers
paracyclophane derivatives
cytotoxicity
anticancer agents
Online Access:https://www.mdpi.com/1424-8247/18/4/473
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