CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway

CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway

BackgroundRadioresistance poses a major therapeutic challenge in ESCC, significantly impacting patient prognosis. CD9, as a crucial membrane regulatory protein, exhibits dual regulatory roles in various cancers, yet its precise mechanism in ESCC radioresistance remains unclear. This study aims to sy...

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Bibliographic Details
Main Authors: Liubing Hou, Zengyao Hao, Ge Zhang, Jiayuan Li, Yu Wang, Xiaoying Xue, Huandi Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
radioresistance
prognostic biomarker
CD9
Akt/GSK3β pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1625120/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1625120/full

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