Efficacy and safety of levothyroxine monotherapy in lowering the risk of cardiovascular disease in older adults with subclinical hypothyroidism: research protocols of a multicenter, open-label, randomized controlled trial

Abstract Objective This multicenter, open-label, randomized controlled trial (RCT) aims to assess the efficacy and safety of levothyroxine monotherapy in lowering the risk of cardiovascular disease (CVD) in untreated older adults with subclinical hypothyroidism (SCH) who are diagnosed according to p...

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Bibliographic Details
Main Authors: Chong Xu, Hui Zhou, Xiaofan Lu, Shuhang Xu, Yu Sun
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Trials
Online Access:https://doi.org/10.1186/s13063-025-08857-z
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