A Facile Synthesis of Some Bioactive Isoxazoline Dicarboxylic Acids via Microwave-Assisted 1,3-Dipolar Cycloaddition Reaction

The microwave-assisted 1,3-dipolar cycloaddition reaction of several aldoximes and dimethyl-2-methylene glutarate in the presence of diacetoxyiodobenzene as an oxidant produced four new isoxazoline-derived dimethyl carboxylates. Saponification followed by acidification of the latter yielded novel is...

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Bibliographic Details
Main Authors: Jessica Master, Shekiel Sydney, Harsha Rajapaske, Malek Saffiddine, Vikiana Reyes, Richard W. Denton
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Reactions
Subjects:
Online Access:https://www.mdpi.com/2624-781X/5/4/57
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