Storage Conditions of Conjugated Reagents Can Impact Results of Immunogenicity Assays

Consistent performance of anti-drug antibody (ADA) assays through all stages of clinical development is critical for the assessment of immunogenicity and interpretation of PK, PD, safety, and efficacy. The electrochemiluminescent assays commonly employed for ADA measurement use drug conjugated with...

Full description

Saved in:
Bibliographic Details
Main Authors: Robert J. Kubiak, Nancy Lee, Yuan Zhu, William R. Franch, Sophia V. Levitskaya, Surekha R. Krishnan, Varghese Abraham, Peter F. Akufongwe, Christopher J. Larkin, Wendy I. White
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/1485615
Tags: Add Tag
No Tags, Be the first to tag this record!