The NF-κB Inhibitor Curcumin Blocks Sepsis-Induced Muscle Proteolysis

We tested the hypothesis that treatment of rats with curcumin prevents sepsis-induced muscle protein degradation. In addition, we determined the influence of curcumin on different proteolytic pathways that are activated in septic muscle (i.e., ubiquitin-proteasome-, calpain-, and cathepsin L-depende...

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Bibliographic Details
Main Authors: Vitaliy Poylin, Moin U. Fareed, Patrick O'Neal, Nima Alamdari, Natasha Reilly, Michael Menconi, Per-Olof Hasselgren
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2008/317851
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