The ACE2 decoy receptor can overcome immune escape by rapid mutating SARS-CoV-2 variants and reduce cytokine induction and clot formation

The ACE2 decoy receptor can overcome immune escape by rapid mutating SARS-CoV-2 variants and reduce cytokine induction and clot formation

Abstract Background The COVID-19 pandemic continues to affect the world in 2025. The rapid mutation of SARS-CoV-2 results in breakthrough infections and diminishes the efficacy of vaccines and anti-viral drugs. The severity of the disease varies across different variants, and the underlying mechanis...

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Bibliographic Details
Main Authors: Ming-Shiu Lin, Tai-Ling Chao, Yu-Chi Chou, Yao Yi, Ci-ling Chen, Kuo-Yen Huang, Sui-Yuan Chang, Pan-Chyr Yang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Biomedical Science
Subjects:
ACE2-Fc
SARS-CoV-2
Spike
Immune escape
Online Access:https://doi.org/10.1186/s12929-025-01156-4
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https://doi.org/10.1186/s12929-025-01156-4

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