Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT
Purpose: To evaluate the intraobserver repeatability and interobserver reproducibility of anterior segment parameters measured by the new YG-100K full-range swept-source optical coherence tomographer (SS-OCT) and compare them with values from the validated CASIA 2 anterior segment optical coherence...
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Elsevier
2025-10-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100025002959 |
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| author | Chak Seng Lei Xinyu Jiang Xinning Yang Qing Wang Kexin Li Rui Ning Giacomo Savini Domenico Schiano-Lomoriello Xingtao Zhou Jinhai Huang |
| author_facet | Chak Seng Lei Xinyu Jiang Xinning Yang Qing Wang Kexin Li Rui Ning Giacomo Savini Domenico Schiano-Lomoriello Xingtao Zhou Jinhai Huang |
| author_sort | Chak Seng Lei |
| collection | DOAJ |
| description | Purpose: To evaluate the intraobserver repeatability and interobserver reproducibility of anterior segment parameters measured by the new YG-100K full-range swept-source optical coherence tomographer (SS-OCT) and compare them with values from the validated CASIA 2 anterior segment optical coherence tomographer (AS-OCT). Methods: In a randomized sequence, the first operator conducted three consecutive measurements with both devices, while a second operator independently conducted three consecutive measurements with only the YG-100K. Each device’s built-in software automatically identified the scleral spur and angle recess. Measured parameters included central corneal thickness (CCT), anterior chamber depth (ACD), angle-to-angle (ATA) distance, anterior chamber width (ACW), lens vault (LV), crystalline lens rise (CLR), lens thickness (LT), trabecular iris angle (TIA), angle open distance (AOD) and trabecular iris space area (TISA). The within-subject standard deviation (Sw), test-retest (TRT) repeatability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated. Bland-Altman plots were assessed inter-device agreement. Results: The YG-100K demonstrated excellent repeatability and reproducibility, evidenced by low Sw, TRT, and CoV values, and ICCs nearing 1.000 (intraobserver ICCs: 0.918−0.998; interobserver ICCs: 0.972−0.998). Comparative analysis revealed good agreement for CCT and ACD. However, ATA and ACW were significantly lower, whereas LT, LV and CLR were slightly higher with YG-100K. Angle measurements between the two devices showed wide 95 % limits of agreement (LoA). Conclusions: This new full-range SS-OCT exhibited high repeatability and reproducibility for anterior segment measurements, confirming its reliability. However, significant differences and wide 95 % LoAs compared to the CASIA 2 suggested that these devices were not interchangeable. |
| format | Article |
| id | doaj-art-1f0bffb0734a45c0ad784635aecfadd3 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-1f0bffb0734a45c0ad784635aecfadd32025-08-20T05:04:59ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-10-015510476310.1016/j.pdpdt.2025.104763Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCTChak Seng Lei0Xinyu Jiang1Xinning Yang2Qing Wang3Kexin Li4Rui Ning5Giacomo Savini6Domenico Schiano-Lomoriello7Xingtao Zhou8Jinhai Huang9Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; NHC Key laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, ChinaUniversity of Shanghai for Science and Technology, School of Health Science and Engineering, Shanghai, ChinaThe Second Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; NHC Key laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; NHC Key laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaIRCCS Bietti Foundation, Rome, ItalyIRCCS Bietti Foundation, Rome, ItalyEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; NHC Key laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, ChinaEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; NHC Key laboratory of Myopia and Related Eye Diseases; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China; Corresponding author at: Eye Institute and Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan University, No.19 Baoqing Road, Xuhui District, Shanghai 200031, China.Purpose: To evaluate the intraobserver repeatability and interobserver reproducibility of anterior segment parameters measured by the new YG-100K full-range swept-source optical coherence tomographer (SS-OCT) and compare them with values from the validated CASIA 2 anterior segment optical coherence tomographer (AS-OCT). Methods: In a randomized sequence, the first operator conducted three consecutive measurements with both devices, while a second operator independently conducted three consecutive measurements with only the YG-100K. Each device’s built-in software automatically identified the scleral spur and angle recess. Measured parameters included central corneal thickness (CCT), anterior chamber depth (ACD), angle-to-angle (ATA) distance, anterior chamber width (ACW), lens vault (LV), crystalline lens rise (CLR), lens thickness (LT), trabecular iris angle (TIA), angle open distance (AOD) and trabecular iris space area (TISA). The within-subject standard deviation (Sw), test-retest (TRT) repeatability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated. Bland-Altman plots were assessed inter-device agreement. Results: The YG-100K demonstrated excellent repeatability and reproducibility, evidenced by low Sw, TRT, and CoV values, and ICCs nearing 1.000 (intraobserver ICCs: 0.918−0.998; interobserver ICCs: 0.972−0.998). Comparative analysis revealed good agreement for CCT and ACD. However, ATA and ACW were significantly lower, whereas LT, LV and CLR were slightly higher with YG-100K. Angle measurements between the two devices showed wide 95 % limits of agreement (LoA). Conclusions: This new full-range SS-OCT exhibited high repeatability and reproducibility for anterior segment measurements, confirming its reliability. However, significant differences and wide 95 % LoAs compared to the CASIA 2 suggested that these devices were not interchangeable.http://www.sciencedirect.com/science/article/pii/S1572100025002959Swept-source optical coherence tomographyAnterior chamber angleRepeatabilityReproducibilityAgreement |
| spellingShingle | Chak Seng Lei Xinyu Jiang Xinning Yang Qing Wang Kexin Li Rui Ning Giacomo Savini Domenico Schiano-Lomoriello Xingtao Zhou Jinhai Huang Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT Photodiagnosis and Photodynamic Therapy Swept-source optical coherence tomography Anterior chamber angle Repeatability Reproducibility Agreement |
| title | Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT |
| title_full | Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT |
| title_fullStr | Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT |
| title_full_unstemmed | Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT |
| title_short | Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT |
| title_sort | repeatability and reproducibility of anterior segment measurements with a new full range ss oct and comparison with an as oct |
| topic | Swept-source optical coherence tomography Anterior chamber angle Repeatability Reproducibility Agreement |
| url | http://www.sciencedirect.com/science/article/pii/S1572100025002959 |
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