Plasma proteomic analysis reveals altered protein abundances in HIV/HBV co-infection individuals with HCC and with liver cirrhosis

Plasma proteomic analysis reveals altered protein abundances in HIV/HBV co-infection individuals with HCC and with liver cirrhosis

Abstract To develop a risk prediction model for hepatocellular carcinoma (HCC) by screening differentially expressed proteins (DEPs) in HIV/HBV coinfected patients with HCC and liver cirrhosis using proteomic techniques. DEPs were identified in plasma from HIV/HBV co-infected patients with HCC and l...

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Bibliographic Details
Main Authors: Yongxi Zhang, Ping Xu, Xingxia Yu, Ke Zhuang, Xien Gui, Rongrong Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Liver cirrhosis
Hepatocellular carcinoma
Human immunodeficiency virus
Lipid metabolism
Apolipoprotein A-1
Transthyretin
Online Access:https://doi.org/10.1038/s41598-025-99072-y
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https://doi.org/10.1038/s41598-025-99072-y

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