Inflammation-related collagen fibril destruction contributes to temporomandibular joint disc displacement via NF-κB activation

Abstract Temporomandibular joint (TMJ) disc displacement is one of the most significant subtypes of temporomandibular joint disorders, but its etiology and mechanism are poorly understood. In this study, we elucidated the mechanisms by which destruction of inflamed collagen fibrils induces alteratio...

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Bibliographic Details
Main Authors: Shengjie Cui, Yanning Guo, Yu Fu, Ting Zhang, Jieni Zhang, Yehua Gan, Yanheng Zhou, Yan Gu, Eileen Gentleman, Yan Liu, Xuedong Wang
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-025-00352-0
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