Belatacept in Kidney Transplantation: Reflecting on the Past, Shaping the Future

Belatacept in Kidney Transplantation: Reflecting on the Past, Shaping the Future

Calcineurin inhibitors (CNIs) are a cornerstone of post-transplant immunosuppressive regimens. However, their use is associated with adverse effects, most notably chronic nephrotoxicity, which remains a leading cause of long-term allograft dysfunction. Belatacept, a selective costimulation blocker,...

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Bibliographic Details
Main Authors: Johan Noble, Juliette Leon, Arnaud Del Bello, Dany Anglicheau, Gilles Blancho, Simon Ville, Lionel Couzi, Philippe Grimbert, Yannick Le Meur, Bruno Moulin, Nassim Kamar, Lionel Rostaing, Florence Herr, Antoine Durrbach, Dominique Bertrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Transplant International
Subjects:
belatacept
kidney transplantation
opportunistic infections
donor-specific antibodies
eGFR
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14412/full
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https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14412/full

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