GSH-responsive polymeric micelles-based augmented photoimmunotherapy synergized with PD-1 blockade for eliciting robust antitumor immunity against colon tumor

Abstract Phototherapy is a promising antitumor modality, which consists of photothermal therapy (PTT) and photodynamic therapy (PDT). However, the efficacy of phototherapy is dramatically hampered by local hypoxia in tumors, overexpression of indoleamine 2,3-dioxygenase (IDO) and programmed cell dea...

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Bibliographic Details
Main Authors: Chenlu Huang, Xinyu Yang, Huidong Li, Li Zhang, Qing Guo, Qingyu Yu, Hai Wang, Linhua Zhang, Dunwan Zhu
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-024-02813-w
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