Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

Prostate cancer (PCa) is one of the most common cancers in men, and for patients with PCa that cannot be surgically resected or treated, androgen suppression therapy often results in significant adverse effects. Recent studies have shown that A3 adenosine receptors (A3ARs) are overexpressed in prost...

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Main Authors: Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:FEBS Open Bio
Subjects:
adenosine
adenosine receptor antagonists
chemotherapy
PC3 cell line
prostate cancer
Online Access:https://doi.org/10.1002/2211-5463.70024
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https://doi.org/10.1002/2211-5463.70024

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