miR-30a enhanced RIG-I-mediated type I interferon antiviral response by targeting USP14

miR-30a enhanced RIG-I-mediated type I interferon antiviral response by targeting USP14

ABSTRACT Type I interferon (IFN) signaling plays a prominent role in the host innate immune defense against viral infection. The regulatory roles of miRNAs on the innate immune response remain to be further explored. Although miR-30a has been implicated in the regulation of various viral life cycles...

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Bibliographic Details
Main Authors: Jikai Zhang, Yiwen Wang, Ningye Sun, Botao Zou, Zijie Wang, Hang Yin, Jiaqian Xie, Banruo Xia, Nan Sun
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
miR-30a
RIG-I
USP14
ubiquitination
innate immunity
antiviral effects
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00188-25
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https://journals.asm.org/doi/10.1128/spectrum.00188-25

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