Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains

Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains

ABSTRACT Resistance to ampicillin and imipenem in Enterococcus faecalis is infrequent. However, the evolution of resistance can occur through prolonged antibiotic exposure during the treatment of chronic infections. In this study, we conducted a long-term evolution experiment using four genetically...

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Bibliographic Details
Main Authors: Paul Ugalde Silva, Charlene Desbonnet, Louis B. Rice, Mónica García-Solache
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
Enterococcus
beta-lactams
drug resistance evolution
antibiotic dependence
c-di-AMP
long-term evolution experiment
Online Access:https://journals.asm.org/doi/10.1128/mbio.02897-24
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https://journals.asm.org/doi/10.1128/mbio.02897-24

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