The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

The Acute Phase of Trypanosoma cruzi Infection Is Attenuated in 5-Lipoxygenase-Deficient Mice

In the present work we examine the contribution of 5-lipoxygenase- (5-LO-) derived lipid mediators to immune responses during the acute phase of Trypanosoma cruzi infection in 5-LO gene knockout (5-LO−/−) mice and wild-type (WT) mice. Compared with WT mice, the 5-LO−/− mice developed less parasitemi...

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Main Authors: Adriana M. C. Canavaci, Carlos A. Sorgi, Vicente P. Martins, Fabiana R. Morais, Érika V. G. de Sousa, Bruno C. Trindade, Fernando Q. Cunha, Marcos A. Rossi, David M. Aronoff, Lúcia H. Faccioli, Auro Nomizo
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/893634
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http://dx.doi.org/10.1155/2014/893634

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