HLA-mismatched stem cell microtransplant prolonged overall survival and promoted immunological reconstitution for multiple myeloma

HLA-mismatched stem cell microtransplant prolonged overall survival and promoted immunological reconstitution for multiple myeloma

BackgroundDespite advances in the treatment of multiple myeloma, a proportion of patients still hardly achieve desired prognosis. Although microtransplant (MST) has proved promising results in treating several hematological malignancies, it has not been studied in multiple myeloma.MethodsWe performe...

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Main Authors: Yangyang Lei, Bo Cai, Zhiqing Liu, Anli Xie, Jianhui Qiao, Yi Wang, Xinrui Chen, Fei Peng, Yingxin Zhao, Jiaxin Chen, Wei Guan, Changlin Yu, Xiao Lou, Kaixun Hu, Ang Zhang, Qiyun Sun, Yajing Huang, Huisheng Ai, Mei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
myeloma
immunotherapies
immunology
micro-transplant
microchimerism
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1509588/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1509588/full

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