Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure

IntroductionThere is growing body of evidence that an enhanced concentration of branched-chain amino acids (BCAAs), as a consequence of an impaired myocardial oxidative metabolism, is involved in the occurrence and progression of heart failure (HF). The purpose of this study was to examine the effec...

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Bibliographic Details
Main Authors: Lucyna Widacha, Joanna Szramel, Zenon Nieckarz, Anna Kurpinska, Ryszard T. Smolenski, Stefan Chlopicki, Jerzy A. Zoladz, Joanna Majerczak
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1568060/full
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