How THC works: Explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1

Summary: Interaction with cannabinoid receptor 1 (CB1) partially determines the bioactivity of the phytocannabinoids. Consequently, there has also been significant effort directed toward preparing synthetic cannabinoids with either enhanced agonistic or antagonistic activity against this receptor. T...

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Bibliographic Details
Main Authors: Farsheed Shahbazi-Raz, Daniel Meister, Azam Mohammadzadeh, John Frederick Trant
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225009678
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