Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking

Abstract Herpes simplex virus type 1 (HSV-1) remodels the host chromatin structure and induces a host-to-virus transcriptional switch during lytic infection. We combine super-resolution imaging and chromosome-capture technologies to identify the mechanism of remodeling. We show that the host chromat...

Full description

Saved in:
Bibliographic Details
Main Authors: Esther González-Almela, Alvaro Castells-Garcia, François Le Dily, Manuel Fernández Merino, Davide Carnevali, Pol Cusco, Luciano Di Croce, Maria Pia Cosma
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60534-6
Tags: Add Tag
No Tags, Be the first to tag this record!