Clinical Outcomes With Notch Inhibitors in Notch‐Activated Recurrent/Metastatic Adenoid Cystic Carcinoma

ABSTRACT Background Adenoid cystic carcinoma (ACC) with NOTCH‐activating mutations presents a clinical challenge due to its poor prognosis. NOTCH inhibitors have emerged as a potential therapy for ACC patients with NOTCH activation. This study aimed to evaluate the efficacy of NOTCH inhibitors in th...

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Bibliographic Details
Main Authors: Camilla O. Hoff, Luana G. deSousa, Flavia Bonini, Eduardo Dal Lago, Kaiwen Wang, Juliana M. Siqueira, Yoshitsugu Mitani, Adel K. El‐Naggar, Renata Ferrarotto
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Online Access:https://doi.org/10.1002/cam4.70663
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