Carbon dot-based treatment for bacterial pneumonia by promoting a PI3K-mediated M1 polarization of macrophages

Carbon dot-based treatment for bacterial pneumonia by promoting a PI3K-mediated M1 polarization of macrophages

Abstract As the incessant emergence of drug-resistant bacterial strains, bacterial pneumonia poses a serious threat to the public health worldwide. There is an urgent need to explore unconventional therapeutic strategies. Carbon dots are usually designed to directly kill bacteria, however, carbon do...

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Bibliographic Details
Main Authors: Xuan Jiang, Jun Wang, Lin Gan, Zengshuai Wu, Tong Wu, Fengyang Li, Xiaowei Xu, Liancheng Lei, Na Li
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Nanobiotechnology
Subjects:
Carbon Dots
Multidrug-resistant
Bacterial pneumonia
PIK3CD
Macrophage polarization
Online Access:https://doi.org/10.1186/s12951-025-03399-7
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https://doi.org/10.1186/s12951-025-03399-7

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