OTUD3 inhibits breast cancer cell metastasis by regulating TGF-β pathway through deubiquitinating SMAD7

Abstract Background Breast cancer (BRCA) is the most common malignant tumor in women, and distant metastasis is an important cause of death. Epithelial mesenchymal transition (EMT) is an important factor in tumor cell metastasis, in which TGF-β signaling pathway plays an important role. SMAD7 can in...

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Bibliographic Details
Main Authors: Chenchen Geng, Ke Dong, Junhua An, Ziqian Liu, Qianqian Zhao, Yanrong Lv
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cancer Cell International
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Online Access:https://doi.org/10.1186/s12935-025-03822-x
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