Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy

Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy

Abstract Many important vascular diseases including neointimal hyperplasia and atherosclerosis are characterized by the endothelial cell (EC) injury-initiated pathological vascular remodeling. However, the endogenous regulatory mechanisms underlying it are not fully understood. The present study inv...

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Main Authors: Bin Jiang, Fan Bai, Yunfu Hu, Yu Ren, Yuan Su, Wanxuan Song, Kunxin Xie, Dongdong Wang, Junlu Pan, Yuying Liu, Yuxin Feng, Xiaoyu Li, Hanwen Zhang, Xudong Zhu, Hui Bai, Qing Yang, Jingjing Ben, Qi Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59644-y
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https://doi.org/10.1038/s41467-025-59644-y

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