Pharmacological regulation of the activity of cytochrome P450 3A4 AND P450 2C9 isoenzymes by vitamins and natural compounds

Pharmacological regulation of the activity of cytochrome P450 3A4 AND P450 2C9 isoenzymes by vitamins and natural compounds

The influence of vitamins with antioxidant properties (vitamins A, E, C), B vitamins (B1, B2, B6) and vitamin-like substances (coenzyme Q10, taurine and L-carnitine) on the enzymes of the first phase of xenobiotic metabolism - cytochromes P450 3A4 and P450 2C9 has been studied. The experiments with...

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Bibliographic Details
Main Authors: E. V. Shikh, A. A. Makhova, V. V. Shumyantseva, O. A. Demidova
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2018-02-01
Series:Регуляторные исследования и экспертиза лекарственных средств
Subjects:
цитохром p450 3a4
цитохром p450 2c9
диклофенак
антиоксиданты
электрохимия
ферментные электроды
витамины a, c, e
витамины группы b
взаимодействие
cytochrome p450 2c9
cytochrome p450 3a4
diclofenac
antioxidants
electrochemistry
enzyme electrodes
a, c, e vitamins
b vitamins
interaction
Online Access:https://www.vedomostincesmp.ru/jour/article/view/105
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