The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity

The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity

Abstract Background As individuals age, the immune system undergoes complex changes, including an increase in the number of CD8 T cells relative to CD4 T cells, a decline in naïve cell production (including T and B cells), and an accumulation of terminally differentiated cells with diminished functi...

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Bibliographic Details
Main Authors: Kate A. Duchowny, Yuan S. Zhang, Rebecca C. Stebbins, Xin Ma, Jaydon Jun Yu Chin, Virginia W. Chang, Allison E. Aiello, Grace A. Noppert
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Immunity & Ageing
Subjects:
Population health
Immunosenescence
Social determinants
Disparities
Mortality
Online Access:https://doi.org/10.1186/s12979-025-00521-z
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https://doi.org/10.1186/s12979-025-00521-z

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