Germline structural variations involving the pediatric brain tumor transcriptome include disease-relevant and ancestry-related genes

Abstract Background Germline Structural Variants (SVs) represent an important source of genetic diversity, in large part due to their influence on gene transcription. It is necessary to systematically catalog germline SVs and their associated impacted genes across different cohorts and tissue and ce...

Full description

Saved in:
Bibliographic Details
Main Authors: Fengju Chen, Yiqun Zhang, Luis F. Paulin, Fritz J. Sedlazeck, Chad J. Creighton
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Acta Neuropathologica Communications
Online Access:https://doi.org/10.1186/s40478-025-02098-6
Tags: Add Tag
No Tags, Be the first to tag this record!