A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway

A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway

Yang Liu,1,2 Guan-nan Liu,1,2 Ya-rong Zha,1 Chen-li Pan,1 Yong-de Xu,3 Hong-wei Li,1 Yue-yue Zang,1 Wan-qi Wang,1 Jun-jie Yao,1 Jun-tao Sun,1,2 Yong Yang,2 Zhi-tao Wei2 1Changchun University of Chinese Medicine, Changchun, Jilin Province, People’s Republic of China; 2Department of Urology, The Affil...

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Bibliographic Details
Main Authors: Liu Y, Liu GN, Zha YR, Pan CL, Xu YD, Li HW, Zang YY, Wang WQ, Yao JJ, Sun JT, Yang Y, Wei ZT
Format: Article
Language:English
Published: Dove Medical Press 2025-05-01
Series:Drug Design, Development and Therapy
Subjects:
diabetes mellitus
erectile dysfunction
ferroptosis
YS-10
ICA II
Nrf2
Online Access:https://www.dovepress.com/a-novel-flavonoid-derivative-of-icariside-ii-ys-10-improves-erectile-d-peer-reviewed-fulltext-article-DDDT
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