VHL type 2B mutations retain VBC complex form and function.

<h4>Background</h4>von Hippel-Lindau disease is characterized by a spectrum of hypervascular tumors, including renal cell carcinoma, hemangioblastoma, and pheochromocytoma, which occur with VHL genotype-specific differences in penetrance. VHL loss causes a failure to regulate the hypoxia...

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Bibliographic Details
Main Authors: Kathryn E Hacker, Caroline Martz Lee, W Kimryn Rathmell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003801&type=printable
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