A Simple NMR‐Based Rule for Stereochemical Assignment of 1,5‐Diols in Polyketides

A Simple NMR‐Based Rule for Stereochemical Assignment of 1,5‐Diols in Polyketides

Abstract Polyketide natural products are a valuable source of inspiration for therapeutic lead compounds, but their diversity and complexity make structure elucidation highly challenging. Here, we report a comprehensive analysis of the relative stereochemical assignment of 1,5‐diol moieties in polyk...

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Bibliographic Details
Main Authors: Max Deering, Malcolm George, Prof. Craig P. Butts, Prof. Varinder K. Aggarwal
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:ChemistryEurope
Subjects:
Natural Products
Structure determination
1H NMR
1,5-diols
Online Access:https://doi.org/10.1002/ceur.202500044
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https://doi.org/10.1002/ceur.202500044

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