Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives

Cuproptosis-related genes and agents: implications in tumor drug resistance and future perspectives

In the field of tumor treatment, drug resistance remains a significant challenge requiring urgent intervention. Recent developments in cell death research have highlighted cuproptosis, a mechanism of cell death induced by copper, as a promising avenue for understanding tumor biology and addressing d...

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Bibliographic Details
Main Authors: Lingwen Xu, Xiaolan Cao, Yuxiao Deng, Bin Zhang, Xinzhi Li, Wentao Liu, Wenjie Ren, Xuan Tang, Xiangyu Kong, Daizhou Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
tumor drug resistance
cuproptosis
copper homeostasis
copper ionophores
chelators
nanodelivery
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1559236/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1559236/full

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