Identification of parthanatos-related molecular subtypes and development of prognostic risk models in ovarian cancer based on multi-omics analysis

Identification of parthanatos-related molecular subtypes and development of prognostic risk models in ovarian cancer based on multi-omics analysis

Abstract Ovarian cancer (OC) remains the most lethal gynecologic malignancy due to late-stage diagnosis, high recurrence rates, and chemoresistance. Parthanatos, a distinct caspase-independent form of programmed cell death mediated by poly (ADP-ribose) (PAR), plays a critical role in DNA damage resp...

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Bibliographic Details
Main Authors: Xiaoying Qi, Changqing Jiang, Ning Wang, Yi Han, Tingting Liu, Liying Huang, Guangjie Yin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Ovarian Research
Subjects:
Parthanatos
Ovarian cancer
Single-cell RNA sequencing
Immune infiltration
TGFBI
Online Access:https://doi.org/10.1186/s13048-025-01726-y
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https://doi.org/10.1186/s13048-025-01726-y

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