Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate

Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate

Liver injury is an independent risk factor for multiple organ dysfunction and high mortality in patients with sepsis. However, the pathological mechanisms and therapeutic strategies for sepsis-associated liver injury have not been fully elucidated. Time-restricted feeding (TRF) is a promising dietar...

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Main Authors: Jing-Juan Hu, Fan Deng, Qi-Shun Sun, Qing-Ming Xiong, Yue Min, Si-Yuan Feng, Ze-Bin Lin, Peng-Han Chen, Zhen Hu, Ling Wu, Xiao-Feng Chen, Sun Xie, Wei-Feng Liu, Cai Li, Ke-Xuan Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Time-restricted feeding
Lactobacillus murinus
3-hydroxybutyrate
PI3K/AKT/mTOR/LPIN1 pathway
ferroptosis
septic liver injury
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2486515
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2486515

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