Design, synthesis, and evaluation of a novel fluorescent probe for competitive fluorescence polarization assay to screen galectin-8 inhibitors

In the present work, we describe the design, synthesis, and evaluation of a galectin-8-binding fluorescent probe designed for a competitive fluorescence polarization (FP) assay for screening new galectin-8N inhibitors. The probe was characterized for its photophysical properties and its binding affi...

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Bibliographic Details
Main Authors: Purić Edvin, Marinović Marina, Kojek Zala, Kahl-Knutson Barbro, Leffler Hakon, Nilsson Ulf J., Anderluh Marko, Mravljak Janez
Format: Article
Language:English
Published: Sciendo 2025-06-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2025-0010
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