Integrated analysis of single-cell and bulk RNA sequencing to construct a CD8+ T cell-related immune gene signature in pancreatic cancer

Background:. Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant tumor that responds poorly to immunotherapy. The pivotal influence of CD8+ T-cell infiltration on immunotherapy has been documented in various solid tumors. However, the specific contribution of CD8+ T cell-associated immune...

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Bibliographic Details
Main Authors: Yuzhi Liu, Fei Xu, Anyi Jiang, Jie Ding, Chungao Li, Ming Quan
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2025-03-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000180
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