PLB2Tau mice are impaired in novel and temporal object recognition and show corresponding traits in brain MRI

Recent clinical trials targeting tau protein aggregation have heightened interest in tau-based therapies for dementia. Success of such treatments depends crucially on translation from non-clinical animal models. Here, we present the age profile of the PLB2Tau knock-in model of fronto-temporal dement...

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Bibliographic Details
Main Authors: Jacques Micheau, Gwenaelle Catheline, Elodie Barse, Bassem Hiba, Anne Marcilhac, Michèle Allard, Bettina Platt, Gernot Riedel
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain Research Bulletin
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Online Access:http://www.sciencedirect.com/science/article/pii/S0361923024002958
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