Advancing immunomodulation in organ transplantation: the therapeutic potential of self-assembled rapamycin nanoparticles in allograft rejection

Advancing immunomodulation in organ transplantation: the therapeutic potential of self-assembled rapamycin nanoparticles in allograft rejection

Abstract Background Transplant rejection remains a significant challenge, necessitating effective post-transplant interventions. Although rapamycin (RAPA) is a recognized immunosuppressant, its utility is limited by poor solubility and delivery efficiency. This study investigates a self-assembly str...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruiqi Sun, Zhi Liang, Ning Wang, Xiaona Chen, Jialing Zhao, Hong Tang, Wentao Zhao, Hangxiang Wang, Shusen Zheng, Penghong Song, Haiyang Xie
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Nanobiotechnology
Subjects:
Pure drug self-assembly system
Organ transplantation
Immune rejection
Immune regulation
Online Access:https://doi.org/10.1186/s12951-025-03498-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12951-025-03498-5

Similar Items