Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice

Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice

Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by lung remodeling induced by chronic inflammation, presenting challenges for effective treatment. Mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) have shown promise in mitigating inflammation and...

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Bibliographic Details
Main Authors: Ting Jin, Xianyang Liu, Guoan Li, Shenghua Sun, Lihua Xie
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
COPD
Mesenchymal stem cells
Transfer RNA-derived small RNA
Lung remodeling
Inflammation
Apoptosis
Online Access:https://doi.org/10.1186/s13287-024-04066-8
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https://doi.org/10.1186/s13287-024-04066-8

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