Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment

Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment

Melioidosis is a serious infectious disease endemic in Southeast Asia, Northern Australia and has been increasingly reported in other tropical and subtropical regions in the world. Percutaneous inoculation through cuts and wounds on the skin is one of the major modes of natural transmission. Despite...

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Bibliographic Details
Main Authors: Joanne Wei Kay Ku, Supatra Tharinee Marsh, Mui Hoon Nai, Kim Samirah Robinson, Daniel Eng Thiam Teo, Franklin Lei Zhong, Katherine A. Brown, Thiam Chye Lim, Chwee Teck Lim, Yunn-Hwen Gan
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
Burkholderia
inflammasome
keratinocyte
melioidosis
skin
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.2011621
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https://www.tandfonline.com/doi/10.1080/22221751.2021.2011621

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