Maculopathy after long-term use of fondaparinux, a heparin mimetic and heparanase inhibitor

Maculopathy after long-term use of fondaparinux, a heparin mimetic and heparanase inhibitor

Purpose: To report maculopathy associated with the long-term use of fondaparinux, a heparin mimetic and inhibitor of the extracellular matrix enzyme, heparanase. Observations: A 41-year-old woman receiving thrice weekly injections of fondaparinux as prophylaxis against deep vein thrombosis for 9 yea...

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Bibliographic Details
Main Authors: Benjamin R. Lin, Erick Rivera-Grana, Wenting Zhou, Mark Barakat, Philip J. Rosenfeld, Janet L. Davis
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Fondaparinux
Pentosan polysulfate
Pigmentary maculopathy
Heparin mimetics
Heparanase inhibitors
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993625000611
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