CFTR expression decreases with age in several airway cell types

CFTR expression decreases with age in several airway cell types

Abstract The mucociliary clearance (MC) system is a vital host defense against infection in the lung. MC system function is dependent on ciliary density, structure, and function and airway surface liquid (ASL) composition and hydration. Animal and human studies indicate that MC rate decreases with a...

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Bibliographic Details
Main Authors: Timothy E. Corcoran, Matthew J. Broerman, Corrine R. Kliment, Cecilia Lo
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
CFTR
Mucus
Mucociliary clearance
Lung aging
Online Access:https://doi.org/10.1038/s41598-024-80108-8
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https://doi.org/10.1038/s41598-024-80108-8

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