Comprehensive bioinformatics and immunohistochemical analyses identify phosphoinositide metabolism and PNPLA7 as potential biomarkers in urological cancers

Comprehensive bioinformatics and immunohistochemical analyses identify phosphoinositide metabolism and PNPLA7 as potential biomarkers in urological cancers

Abstract Phosphoinositides (PI) and their metabolic enzymes are known to be involved in cellular processes associated with the hallmarks of cancer. The impact of PI metabolism-related components on urinary tract (or urological) cancers, however, remains unexplored. Considering this, herein, we perfo...

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Bibliographic Details
Main Authors: Yinhao Chen, Mingde Gao, Peng Chen, Amit Sharma, Maria Fitria Setiawan, Maria A. Gonzalez-Carmona, Xiaolin Wang, Ingo G. H. Schmidt-Wolf
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Urological cancers
Phosphoinositide metabolism
Machine learning
Bioinformatics
Risk stratification
Online Access:https://doi.org/10.1038/s41598-025-97118-9
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https://doi.org/10.1038/s41598-025-97118-9

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