Low molecular weight fucoidan differentiation media enhances quality and extents shelf life of 3D human skin model

Low molecular weight fucoidan differentiation media enhances quality and extents shelf life of 3D human skin model

Abstract In vitro three-dimensional artificial human skin models (3D-HSMs) have revolutionized research in drug testing, disease modeling, and cosmetic evaluations. However, preserving the shelf-life of 3D-HSM during extended culture remains a challenge. Our previous study uncovered the anti-prolife...

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Bibliographic Details
Main Authors: Yun-Mi Jeong, Won-Soo Yun, Jin-Hyung Shim
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Low-molecular-weight fucoidan
An alternative to animal testing
Human cell-based 3D-full-thickness artificial human skin models
Long-term cultivation
Prolonged shelf life
Online Access:https://doi.org/10.1038/s41598-025-05461-8
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https://doi.org/10.1038/s41598-025-05461-8

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